Verified active February 2, 2026

Key Highlights

  • .406 Ventures has a proven track record of identifying and investing in high-growth startups across healthcare, data + AI, and cybersecurity sectors.
  • The firm's lead investments have resulted in significant acquisitions by major industry players, demonstrating its ability to drive value and success for its portfolio companies.
  • Founded in 2005, .406 Ventures has nearly two decades of experience in early-stage investments, providing a wealth of knowledge and expertise to its portfolio companies.
  • The firm's strategic approach and deep industry understanding enable it to support visionary entrepreneurs and drive innovation in key sectors.
  • .406 Ventures' commitment to long-term value creation and its focus on emerging technologies make it an attractive partner for startups seeking growth and success.

About .406 Ventures

.406 Ventures is a Boston-based venture capital firm with over $1.4 billion under management and nearly two decades of experience in early-stage investments. The firm specializes in healthcare, data + AI, and cybersecurity sectors, backing visionary entrepreneurs. Notable lead investments include AbleTo, Carbon Black, Cloud Health, Health Dialog, Iora Health, Mineral Tree, and Veracode. These companies have been acquired by industry giants such as Optum, VMWare, BUPA, One Medical/Amazon, Global Payments, and CA Technologies.

Founded in 2005, .406 Ventures has built a reputation for identifying and supporting innovative startups with high growth potential. The firm's strategic approach and deep industry expertise have enabled it to drive significant value for its portfolio companies and investors.

The firm's success is driven by a commitment to innovation, a deep understanding of emerging technologies, and a focus on long-term value creation. .406 Ventures continues to be a key player in the venture capital landscape, supporting the next generation of tech leaders.

Company Facts

Ownership Private Company

Connect with .406 Ventures

Why Contact .406 Ventures?

B2B professionals should contact .406 Ventures for strategic investment opportunities in healthcare, data + AI, and cybersecurity sectors. The firm's extensive experience and network can provide valuable support and growth potential for innovative startups.

Who Should Contact .406 Ventures for Business?

Sales teams selling innovative healthcare, data + AI, and cybersecurity solutions, recruiters seeking roles in venture capital, and partners offering investment opportunities should reach out to .406 Ventures.

Categories

  • Venture Capital
  • Early-Stage Investments
  • Healthcare Startups
  • Data + AI
  • Cybersecurity
  • Innovative Entrepreneurs
  • Acquisitions
  • Growth Potential
  • Strategic Investment
  • Industry Expertise

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Frequently Asked Questions

What does .406 Ventures do?
.406 Ventures is a venture capital firm that focuses on early-stage and growth investments, specifically targeting enterprise-related opportunities and category-defining companies.
How many employees does .406 Ventures have?
.406 Ventures has approximately 111 employees.
Where is .406 Ventures headquartered?
The company is headquartered in Boston, Massachusetts.
What industry is .406 Ventures in?
.406 Ventures operates in Healthcare Technology, Data + AI Solutions, Cybersecurity Ventures.
When was .406 Ventures founded?
.406 Ventures was founded in 2005.
What is the email format at .406 Ventures?
.406 Ventures uses the email format flast@406ventures.com.
Is .406 Ventures still active?
Yes, .406 Ventures was verified as an active company on February 2, 2026. Data Surfer regularly validates company information to ensure accuracy.
How do I sell to .406 Ventures?
Research .406 Ventures's priorities and goals, identify the right decision makers and champions, monitor for buying signals, and reach out at the right time with verified contact details. Learn how Data Surfer helps.

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Last verified: February 2, 2026

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