.406 Ventures is a Boston-based venture capital firm with over $1.4 billion under management and nearly two decades of experience in early-stage investments. The firm specializes in healthcare, data + AI, and cybersecurity sectors, backing visionary entrepreneurs. Notable lead investments include AbleTo, Carbon Black, Cloud Health, Health Dialog, Iora Health, Mineral Tree, and Veracode. These companies have been acquired by industry giants such as Optum, VMWare, BUPA, One Medical/Amazon, Global Payments, and CA Technologies.
Founded in 2005, .406 Ventures has built a reputation for identifying and supporting innovative startups with high growth potential. The firm's strategic approach and deep industry expertise have enabled it to drive significant value for its portfolio companies and investors.
The firm's success is driven by a commitment to innovation, a deep understanding of emerging technologies, and a focus on long-term value creation. .406 Ventures continues to be a key player in the venture capital landscape, supporting the next generation of tech leaders.
| Ownership Private Company |
B2B professionals should contact .406 Ventures for strategic investment opportunities in healthcare, data + AI, and cybersecurity sectors. The firm's extensive experience and network can provide valuable support and growth potential for innovative startups.
Sales teams selling innovative healthcare, data + AI, and cybersecurity solutions, recruiters seeking roles in venture capital, and partners offering investment opportunities should reach out to .406 Ventures.
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Last verified: February 2, 2026
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